Pap Testing as Primary Screening
HPV Testing and the Pap Test
In 2001, HPV DNA testing was approved for ASC-US triage, the reflex testing of pap tests interpreted as ASC-US. In 2003, HPV DNA testing received expanded labeling to be used as a co-test with the pap in women over the age of 30. Although HPV testing is not a replacement for cytology, it does provide important adjunctive information that can be useful in managing patients.
HPV testing with the pap test: out of the vial
The ThinPrep Pap Test is the only liquid-based pap test FDA-approved for HPV DNA testing directly from the collection vial.
What HPV testing can do
In the era of HPV testing, knowledge of a patient's current state of cervical health remains critical. When used together, pap testing and HPV testing provide you and your patient with detailed information.
HPV testing provides important information about whether a patient has an HPV infection with any of the 14 high-risk HPV types. This information can be useful in managing patients with inconclusive results.
|HPV Testing||Cytology Screening|
|Determines the presence of a high-risk strain of HPV||Determines the presence of abnormal cells on the cervix|
|Useful in predicting the patient's risk of developing cervical cancer if the strain is persistent||Useful in confirming precancerous or cancerous cells at a single point in time|
|Indicated as an adjunctive test to be performed as reflex testing to an ASC-US pap test or for co-testing with the pap for women over the age of 301||Indicated as the primary test for cervical cancer screening|
1. Digene Hybrid Capture® 2 Package Insert. QIAGEN Group, Netherlands.